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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q15121
USC-OGP 2-DE database
:
Q15121
Q15121
General information about the entry
View entry in simple text format
Entry name
PEA15_HUMAN
Primary accession number
Q15121
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Astrocytic phosphoprotein PEA-15; AltName: Full=15 kDa phosphoprotein enriched in astrocytes; AltName: Full=Phosphoprotein enriched in diabetes; Short=PED;.
Gene name
Name=PEA15
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1333
:
pI=4.59; Mw=16158
Cross-references
UniProtKB/Swiss-Prot
Q15121; PEA15_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
PEA15_HUMAN
Primary accession number
Q15121
Secondary accession number(s)
B1AKZ3 O00511
Sequence was last modified on
July 3, 2003 (version 2)
Annotations were last modified on
March 15, 2017 (version 148)
Name and origin of the protein
Description
RecName: Full=Astrocytic phosphoprotein PEA-15; AltName: Full=15 kDa phosphoprotein enriched in astrocytes; AltName: Full=Phosphoprotein enriched in diabetes; Short=PED;
Gene name
Name=PEA15
Encoded on
Name=PEA15
Keywords
3D-structure
;
Alternative splicing
;
Apoptosis
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Phosphoprotein
;
Reference proteome
;
Sugar transport
;
Transport
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X86809; CAA60499.1
; -; mRNA
EMBL
Y13736; CAA74076.1
; -; mRNA
EMBL
AF153274; AAD56775.1
; -; Genomic_DNA
EMBL
AF153273; AAD56775.1
; JOINED; Genomic_DNA
EMBL
AK095879; BAG53155.1
; -; mRNA
EMBL
AL121987; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AL139011; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
CH471121; EAW52735.1
; -; Genomic_DNA
EMBL
BC002426; AAH02426.1
; -; mRNA
EMBL
BC022554; AAH22554.1
; -; mRNA
EMBL
BT007252; AAP35916.1
; -; mRNA
CCDS
CCDS1199.1; -. [Q15121-1]
; .
CCDS
CCDS72954.1; -. [Q15121-2]
; .
PIR
S55384; S55384
; .
RefSeq
NP_001284505.1; NM_001297576.1. [Q15121-2]
; .
RefSeq
NP_001284506.1; NM_001297577.1. [Q15121-1]
; .
RefSeq
NP_001284507.1; NM_001297578.1
; .
RefSeq
NP_003759.1; NM_003768.4. [Q15121-1]
; .
RefSeq
XP_006711662.1; XM_006711599.2. [Q15121-1]
; .
UniGene
Hs.517216; -
; .
PDB
4IZ5; X-ray
; 3.19 A; E/F/G/H=1-130
PDB
4IZA; X-ray
; 1.93 A; B=1-96
PDBsum
4IZ5; -
; .
PDBsum
4IZA; -
; .
ProteinModelPortal
Q15121; -
; .
SMR
Q15121; -
; .
BioGrid
114230; 17
; .
IntAct
Q15121; 13
; .
MINT
MINT-141556; -
; .
STRING
9606.ENSP00000353660; -
; .
iPTMnet
Q15121; -
; .
PhosphoSitePlus
Q15121; -
; .
BioMuta
PEA15; -
; .
DMDM
32470612; -
; .
EPD
Q15121; -
; .
MaxQB
Q15121; -
; .
PaxDb
Q15121; -
; .
PeptideAtlas
Q15121; -
; .
PRIDE
Q15121; -
; .
TopDownProteomics
Q15121-1; -. [Q15121-1]
; .
DNASU
8682; -
; .
Ensembl
ENST00000360472; ENSP00000353660
; ENSG00000162734. [Q15121-1]; .
Ensembl
ENST00000368076; ENSP00000357055
; ENSG00000162734. [Q15121-2]; .
GeneID
8682; -
; .
KEGG
hsa:8682; -
; .
UCSC
uc001fvk.4; human. [Q15121-1]
; .
CTD
8682; -
; .
DisGeNET
8682; -
; .
GeneCards
PEA15; -
; .
HGNC
HGNC:8822; PEA15
; .
HPA
HPA028356; -
; .
MIM
603434; gene
; .
neXtProt
NX_Q15121; -
; .
OpenTargets
ENSG00000162734; -
; .
PharmGKB
PA33166; -
; .
eggNOG
KOG3573; Eukaryota
; .
eggNOG
ENOG410ZQIE; LUCA
; .
GeneTree
ENSGT00390000000230; -
; .
HOGENOM
HOG000049048; -
; .
HOVERGEN
HBG053557; -
; .
InParanoid
Q15121; -
; .
OMA
SPVMAEY; -
; .
OrthoDB
EOG091G0TNX; -
; .
PhylomeDB
Q15121; -
; .
TreeFam
TF332405; -
; .
Reactome
R-HSA-112409; RAF-independent MAPK1/3 activation
; .
Reactome
R-HSA-5673001; RAF/MAP kinase cascade
; .
SignaLink
Q15121; -
; .
SIGNOR
Q15121; -
; .
ChiTaRS
PEA15; human
; .
GeneWiki
PEA15; -
; .
GenomeRNAi
8682; -
; .
PMAP-CutDB
Q15121; -
; .
PRO
PR:Q15121; -
; .
Proteomes
UP000005640; Chromosome 1
; .
Bgee
ENSG00000162734; -
; .
CleanEx
HS_PEA15; -
; .
ExpressionAtlas
Q15121; baseline and differential
; .
Genevisible
Q15121; HS
; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0005875; C:microtubule associated complex
; NAS:UniProtKB; .
GO
GO:0005634; C:nucleus
; IDA:HPA; .
GO
GO:0000187; P:activation of MAPK activity
; TAS:Reactome; .
GO
GO:0006915; P:apoptotic process
; IEA:UniProtKB-KW; .
GO
GO:0008643; P:carbohydrate transport
; IEA:UniProtKB-KW; .
GO
GO:0000077; P:DNA damage checkpoint
; IEA:InterPro; .
GO
GO:0000165; P:MAPK cascade
; TAS:Reactome; .
GO
GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
; IDA:UniProtKB; .
GO
GO:0046325; P:negative regulation of glucose import
; IDA:UniProtKB; .
GO
GO:1902043; P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
; IEA:Ensembl; .
GO
GO:0043278; P:response to morphine
; IEA:Ensembl; .
GO
GO:0006810; P:transport
; TAS:ProtInc; .
CDD
cd08338; DED_PEA15
; 1; .
Gene3D
1.10.533.10; -
; 1; .
InterPro
IPR011029; DEATH-like_dom
; .
InterPro
IPR001875; DED_dom
; .
InterPro
IPR029546; PEA15
; .
PANTHER
PTHR15094; PTHR15094
; 1; .
Pfam
PF01335; DED
; 1; .
SMART
SM00031; DED
; 1; .
SUPFAM
SSF47986; SSF47986
; 1; .
PROSITE
PS50168; DED
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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